Download 31st Hemophilia Symposium Hamburg 2000: Epidemiology by I. Scharrer (auth.), Professor Dr. med. Inge Scharrer, PDF

By I. Scharrer (auth.), Professor Dr. med. Inge Scharrer, Professor Dr. med. Wolfgang Schramm (eds.)

Some 23. five% of all individuals and sufferers of remedy facilities accomplished the questionnaire. One extraordinary truth is that participation used to be maximum among aged sufferers with serious hemophilia, while basically 12. 2% of kinfolk replied. review of the implications printed that almost all of individuals desire deal with­ ment in a hemophilia therapy heart with a excessive attractiveness, while purely 2. 7% think of therapy in a really good perform to be adequate. the explanations for which are the need of the 24-h-availability of a doctor, ordinary certified exam of joints and muscular tissues, documentation of product batches, laboratory exams and sturdy cooperation with different colleges. As many as sixty eight. nine% of the sufferers occasionally shuttle greater than 2 hundred km. What definitely performs a task here's belief within the therapy heart and its physicians, for it really is obvious that regardless of the truth that seventy four. three% re­ quested standardized remedy regimens for all therapy facilities, in basic terms approximately 20% might swap to a closer heart. therapy with issue concentrates is mostly thought of to be very secure. that's to claim, fifty eight. 1 % regard recombinant items to be very secure, while merely 24. three% think this for plasma items. in comparison, there have been frequently no significant transformations saw concerning final result (factor intake, period of deal with­ ment). bring up in greatest garage temperature (47. 2%) and half-life (73%) have been the main widespread solutions to the query of what gains the goods should still have.

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Extra resources for 31st Hemophilia Symposium Hamburg 2000: Epidemiology Inhibitors in Hemophilia Therapy and Monitoring of Bleeds in Acute and Intensive Care Medicine Pediatric Hemostaseology Case Reports

Sample text

774 Table 2. 2 100 100 Table 3. 6 100 Total Hemophilia 2000 - the Annual Survey of the Austrian Hemophilia Centers 17 Table 4. K. Hartl et al. 8%) from hemophilia B; other bleeding disorders in 42 patients and missing information on type of bleeding disorder in 60 patients. In comparison to the Austrian population we have one PwH in 10,182 male Austrians, respectively one person with hemophilia A in 11,813, and one with hemophilia Bin 73,774 males. The relation of patients with mild hemophilia to patients with the severe form is, in hemophilia A as well as in B, similar, the relation of hemophilia A to hemophilia B is according to the literature.

Distribution of HIV-infected patients Causes of Death In the 99100 period a total of 20 patients were reported dead with the distribution of causes of death given in Table 4. Since the beginning of the survey in 1982 a total of 654 patients have been reported dead. As compared to the peak of 60 deaths in the 94/95 period a decrease of 66,7% occurred in the 99/00 period. The development of mortality and causes of death since 82/83 are depicted in Fig. 7. Up to 1995 the number of AIDS-related deaths increased continuously with decline taking place since.

Kornhuber. Immune tolerance therapy on paediatric hemophiliacs with factor VIII inhibitors: 14 years follow-up. Haemophilia 1995; 1: 24-32 11. G. Hodge, R. Flower and P. Han. Effect of factor VIII concentrate on leucocyte cytokine production: characterization of TGF-beta as an immunomodulatory component in plasma- derived factor VIII concentrate. Br J Haematol1999; 106: 784-91 12. M. Mayumi, T. Kuritani, H. Kubagawa and M. D. Cooper. IgG subclass expression by human B lymphocytes and plasma cells: B lymphocytes precommitted to IgG subclass can be preferentially induced by polyclonal mitogens with T cell help.

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