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The authors underscore the fact that this disease is more common than previously thought, and they stress the importance of identifying it in patients with newly diagnosed PH. Moores LK, Holley AB. Computed tomography pulmonary angiography and venography: diagnostic and prognostic properties. Semin Respir Crit Care Med 2008; 29:3−14 An up-to-date review of the diagnostic accuracy and utility, as well as the prognostic features, of spiral CT angiography and venography. Moores LK, Jackson WL Jr, Shorr AF, et al.

29 7/10/09 8:03:54 PM is a key contributor. Platelets likely play an important role as procoagulants by increasing the platelet release of serotonin, vascular endothelial growth factor, and platelet-derived growth factor. Clinical Features PH frequently presents with nonspecific symptoms (Table 5). The most common symptoms are dyspnea on exertion, fatigue, and syncope, resulting from reduced cardiac output during activity. Patients may also occasionally present with anginalike chest pain with normal coronary arteries.

JAMA 2005; 293:2012−2017 A negative CT scan finding is as accurate as pulmonary angiography in ruling out suspected PE. A negative CT scan finding in a low-risk patient rules out PE, whereas a negative CT scan finding in a high-risk patient may require further confirmation. Rubin LJ. American College of Chest Physicians. Diagnosis and management of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines. Chest 2004; 126(suppl):75S−105S In this brief introduction to the guidelines, Dr.

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