Download Cilia and Mucus: From Development to Respiratory Defense by Matthias Salathe PDF

By Matthias Salathe

This ebook info advances in study relating to cilia, mucus, and mucociliary clearance, reading alterations in mucus expression and goblet mobile metaplasia, and assessing the facility of the mucociliary method to answer abnormalities. acknowledges that cilia and dynein fingers play pivotal roles in constructing mammalian embryos!Examines the function of genetics in common and irregular ciliary function!Discussing medical basics, present diagnostic concepts, and clinically validated remedies, Cilia and Mucus analyzes the law of ciliary waves on the mobile point considers irregularities of higher and reduce airlines and cilia in structures of the physique explores power modulators of airway mucin secretion proposes a singular treatment for airway hypersecretion because of the epidermal development issue cascade clarifies gamma digital camera imaging to degree mucociliary clearance describes the impression of purinergic receptors and dry powder mannitol on airway passages and extra! With contributions from over a hundred foreign researchers and clinicians, and containing over 1300 references, drawings, photos, tables, and equations, Cilia and Mucus is a special single-source reference for pulmonologists, physiologists, immunologists, allergists, otolaryngologists, pediatricians, microbiologists, easy scientists, and graduate and clinical institution scholars in those disciplines.

Show description

Read Online or Download Cilia and Mucus: From Development to Respiratory Defense PDF

Best pulmonary & thoracic medicine books

Inhalation Toxicology, Second Edition

Written via across the world well-known scientists from educational, commercial, and governmental sectors, Inhalation Toxicology, moment variation info the equipment and fabrics utilized in the theoretical and utilized elements of inhalation toxicology. The editors emphasize the connection among the breathing procedure and toxicology of inhaled elements and look at tools and measurements for bettering our knowing of the fundamental mechanisms of results.

Interpretation of Pulmonary Function Tests

Interpretation of Pulmonary functionality checks, 4th version offers sensible, clinically proper assurance of all kinds of pulmonary functionality checking out because it applies to a number of sickness stipulations. it really is geared toward any reader with a uncomplicated wisdom of pulmonary body structure and gives an effective foundation for administering and reading those assessments.

Pulmonary Circulation: Diseases and Their Treatment

Pulmonary circulate offers physicians with a greater knowing of the constitution, functionality and pathophysiology of the pulmonary flow. It presents entire insurance from analysis and medical evaluate of sufferers with pulmonary high blood pressure to imaging innovations, problems and therapy.

Critical Care Medicine: The Essentials

Perfect for college kids in severe care rotations and citizens, this concise, useful instruction manual offers the necessities of clinical and surgical severe care in an easy-to-read structure. The authors succinctly clarify the pathophysiology underlying medical problems and the foremost ideas of prognosis and sufferer administration, emphasizing reasonable ways.

Extra resources for Cilia and Mucus: From Development to Respiratory Defense

Example text

Keeping the beat: form meets function in the Chlamydomonas flagellum. Bioessays 17:847–854, 1995. 2. RE Stevens. Ciliogenesis in sea urchin embryos—a subroutine in the program of development. Bioessays 17:331–340, 1995. 3. LA Perkins, EM Hedgecock, JN Thomson, JG Culotti. Mutant sensory cilia in the nematode Caenorhabditis elegans. Dev Biol 117:456–487, 1986. 4. KA Johnson, JL Rosenbaum. Polarity of flagellar assembly in Chlamydomonas. J Cell Biol 19:1605–1611, 1992. 5. KG Kozminski, KA Johnson, P Forscher, JL Rosenbaum.

Mutant sensory cilia in the nematode Caenorhabditis elegans. Dev Biol 117:456–487, 1986. 4. KA Johnson, JL Rosenbaum. Polarity of flagellar assembly in Chlamydomonas. J Cell Biol 19:1605–1611, 1992. 5. KG Kozminski, KA Johnson, P Forscher, JL Rosenbaum. A motility in the eukaryotic flagellum unrelated to flagellar beating. Proc Natl Acad Sci USA 90:5519–5523, 1993. 6. JL Rosenbaum, DG Cole, DR Diener. Intraflagellar transport: the eyes have it. J Cell Biol 144(3):385–388, 1999. 7. RL Morris, JM Scholey.

CONCLUSIONS Our data argue that kinesin-II drives the transport of IFT rafts in the anterograde direction from the neuronal cell body, out along the dendrite, to its final destination at the tip of the sensory cilium. Then, CHE-3 cytoplasmic dynein retrieves both the anterograde motor, kinesin-II, and its associated IFT raft cargo from the ciliary tip back to the transition zone to replenish the available pools of anterograde motor and raft particles. The fact that kinesin-II, OSM-1, and OSM-6 all accumulate at the transition zone suggests that this region serves as a ‘‘loading dock’’ for IFT rafts and the specific cargo that they may be carrying.

Download PDF sample

Rated 4.46 of 5 – based on 25 votes