Download Clinical Reproductive Medicine and Surgery by Tommaso Falcone MD, William Hurd MD PDF

By Tommaso Falcone MD, William Hurd MD

Scientific Reproductive medication and surgical procedure is the hot, definitive source in reproductive medication. This particular textual content bargains particular dialogue on either the scientific and surgical administration of reproductive problems, in addition to assurance of linked imaging modalities. integrated are chapters on Reproductive Genetics, administration of Endometriosis (including interventional radiology), Ultrasonography and Sonohysterography, renovation of Fertility, and Recurrent being pregnant Loss. The e-book additionally gains an accompanying DVD with extra photographs and video loops. A source each practitioner drawn to Reproductive Endocrinology and Infertility needs!Offers unique dialogue of scientific and surgical administration of reproductive problems ... No different textual content deals assurance of either scientific and surgical administration in a single resource.Covers gynecologic issues that impression fertility--an vital element of determining fertility matters, no longer incorporated in significant competitionSection on easy reproductive biology ... now not overly designated -- Written for a clinician to appreciate how you can perform reproductive medicineSection on reproductive imaging ... distinct to this article - contains US and MRI of the reproductive organsAlgorithm in each one bankruptcy ... 4-color all through ... Demonstrates the suitable medical research and administration ... deals appealing format and most sensible perspectives of surgical proceduresPerform reproductive surgical procedure strategies with step by step assistance on intrauterine gadget insertion and laparoscopic surgical procedure with specified photographs and video clips at the accompanying dvd

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Example text

Qxp 1/26/07 10:19 AM Page 19 Chapter 2 Ovarian Hormones Theca cells Cholesterol LH Corpus luteum Δ4 pathway CYP11A (P450scc) Pregnenolone Δ5 pathway 3βHSD CYP17 (P450c17) Progesterone 17OH Pregnenolone CYP17 17,20 lyase CYP17 17OH Progesterone DHEA 3βHSD CYP17 CYP21 CYP21 17βHSB 11-Deoxycorticosterone CYP11 11 Deoxycortisol Androstenedione Testosterone CYP19 (P450arom) CYP11B1 FSH CYP19 17βHSB Corticosterone Cortisol Estrone Estradiol Granulosa cells 18-OH Corticosterone Aldosterone Adrenal gland Figure 2-2 Steroid hormone biosynthesis pathways in the ovary.

These cells responsive to LH and augmenting progesterone secretion. Progesterone then increases FSH release in midcycle. Biochemistry and Biosynthesis The anterior pituitary produces three glycoprotein hormones: LH, FSH, and thyrotropin-stimulating hormone (TSH), all of which share a similar biochemical structure. Each consists of a heterodimer of two noncovalently linked protein subunits, αβ. Each subunit is cysteine-rich and contains multiple disulfide linkages (Fig. 2-9). 200,201 The α subunit is common to all three hormones, whereas the β subunit is unique.

134 As such, it is unlikely to replace testicular biopsy in the evaluation of male infertility. Activins 26 Activins are made up of dimers of the inhibin β subunit (βAβA, βAβB, or βBβB) and have a molecular weight of approximately 25 kDa (see Fig. 135 They are predominantly produced by the granulosa cells of the ovary. Activin/inhibin mRNA and protein have also been detected in extragonadal sources, including the placental trophoblast and decidua, testes, adrenal cortex, brain, spinal cord, and anterior pituitary.

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